|Bisphenol A Myths
Myth: BPA Causes Cancer.
Reality: Based on sound, robust scientific evidence, some government bodies around the world have concluded that bisphenol A (BPA) is not carcinogenic in humans. In 2008, a comprehensive European Union risk assessment reviewed all relevant scientific evidence and concluded that "BPA does not possess any significant carcinogenic potential."
Bisphenol A is not a carcinogen; that is, it does not cause or induce cancer in laboratory animals. One of the most thorough studies in this area was performed by the U.S. National Toxicology Program. Based on lifetime exposure cancer bioassays, the authors found that "there was no convincing evidence that bisphenol A was carcinogenic for rats or mice of either sex" (NTP Technical Report on the Carcinogenesis Bioassay of Bisphenol A. National Toxicology Program. 1982. Technical Report Series No. 215. Summary and full report available at: NTP).
The International Agency for Research on Cancer and the United States Environmental Protection Agency's National Center for Environmental Assessment have well-established guidelines and criteria for the assessment of carcinogenic potential. As described in a recent peer-reviewed publication, a panel of experts has applied these guidelines and criteria to the assessment of a large body of scientific evidence that is relevant to the potential for BPA to cause cancer (An Evaluation of the Possible Carcinogenicity of Bisphenol A to Humans. Haighton, L.A., et al. 2002. J. Reg. Toxicol. Pharmacol. 35: 238-254. Abstract available at: Science Direct). The evidence the panel reviewed included metabolic data, genetic toxicity studies, long-term toxicity/carcinogenicity studies and estimates of consumer exposure. After a thorough review of scientific evidence from numerous studies, the researchers concluded that "BPA is not a carcinogenic risk to humans." The panel also concluded that, as currently used, human exposure to BPA is "trivial."
Among these studies were the lifetime exposure cancer bioassays conducted in rats and mice by the U.S. National Toxicology Program (NTP, 1982), which found no convincing evidence in either of the bioassays that BPA was carcinogenic. The weight of scientific evidence from all of these studies indicates that BPA is not carcinogenic. The panel also concluded that, as currently used, human exposure to BPA is "trivial." (Haighton et al., 2002).
In addition, the European Union concluded in their comprehensive risk assessment on BPA that BPA is without mutagenic or genotoxic activity in vivo (EU RAR, 2003 - PDF).
Watch Steve Hentges, Ph.D., from the American Chemistry Council discuss studies on BPA and cancer.
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