Toxicology is the study of the harmful actions of agents
on biological mechanisms. The toxicological effects
of bisphenol A are well understood. One of the most
extensively tested materials in use today, BPA exhibits
toxic effects only at very high exposures.
| CARCINOGENICITY |
|
| NTP Technical Report on the Carcinogenesis
Bioassay of Bisphenol A. National Toxicology Program.
1982. Technical Report Series No. 215. Summary and
full report available at: NTP |
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| An Evaluation of the Possible Carcinogenicity
of Bisphenol A to Humans. Haighton, L.A., et al.
2002. J. Reg. Toxicol. Pharmacol. 35: 238-254. Abstract
available at: Science
Direct |
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| REPRODUCTIVE
AND DEVELOPMENTAL |
|
Weight of the Evidence Evaluation of
Low-Dose Reproductive and
Developmental Effects of Bisphenol A. Gray, G. M.,
et al. 2004. Human
and Ecological Risk Assessment. 10(5):875-921. Copyright
2004 From Human and Ecological Risk Assessment by
George M. Gray. Reproduced by permission of Taylor
& Francis, Inc., http://www.taylorandfrancis.com.
Full
Text (194kb, PDF) |
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|
| The Developmental Toxicity of Bisphenol
A in Rats and Mice. Morrissey, R.E. et al. 1987.
Fund. Appl. Toxicol. 8: 571-582. Originally published
by Oxford University Press. Full
text (984kb, PDF) |
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|
| Three-Generation Reproductive Toxicity
Study of Dietary Bisphenol A in CD Sprague-Dawley
Rats. Tyl, R.W., et al. 2002. Toxicological Sciences.
68(1):121-146. Abstract and full text available
at: Oxford
Jounals Online |
| |
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| Rat Two-Generation Reproductive Toxicity
Study of Bisphenol-A. Ema, M. 2001. Reproductive
Toxicology. 15(5):505-523. Abstract available at:
Science
Direct |
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| ENDOCRINE
ACTIVITY |
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| Normal Reproductive Organ Development
in CF-1 Mice Following Prenatal Exposure to Bisphenol
A. Cagen, S.Z. et al. 1999. Toxicol. Sci. 50:36-44.
Full
Text (128kb, PDF) |
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| Normal Reproductive Organ Development
in Wistar Rats Exposed to Bisphenol A in Drinking
Water. Cagen, S.Z. et al. 1999. Regul. Toxicol.
Pharmacol. 30(2 Pt 1):130-9. Abstract available
at: Science
Direct |
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| PHARMACOKINETICS |
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| The Relative Bioavailability and Metabolism
of Bisphenol A in Rats Is Dependent upon the Route
of Administration. Pottenger, L.H. et al. 2000.
Toxicol. Sci. 54(1):3-18. Abstract and full text
available at: Oxford
Journals Online |
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| To obtain reprints of specific papers,
contact the publisher directly. |
